Using the Cervex-Brush Combi slightly more lesions were detected (three versus two low-grade squamous intraepithelial lesions), and resulted in the detection of more atypical squamous cells of undetermined significance (six versus three). The use of the Cervex-Brush Combi, however, resulted in a two- to threefold increase in the number of sampled endocervical cells (P < 0.00001). The mean number of sampled squamous cells did not differ between the two brush types (54 963 versus 54 595 cells). All 200 slides were read by the FocalPoint and screened by guided screening using slide wizards. Using either the Cervex-Brush or the Cervex-Brush Combi 100 consecutive SurePath LBC samples were collected using each brush type. The objective of this study was to analyse and to compare the Cervex-Brush Combi with the Cervex-Brush for the collection of squamous and endocervical cells, human papillomavirus (HPV) typing/quantification and disease detection in SurePath LBC. The new Rovers Cervex-Brush Combi combines the advantages of the Cervex-Brush with the EndoCervex-Brush increasing sampling of the endocervical canal. ![]() Together with SurePath LBC, various collecting devices can be utilized, among which the Cervex-Brush is the most widely used. Liquid-based cytology (LBC) for cervical screening is becoming increasingly used.
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